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Heterogeneity
and inconsistency are the two major problems of the tissue arrays made from
donor paraffin-embedded tissue blocks that are collected from multiple pathology
centers. These problems are closely associated with different fixation and
processing methods/standards applied in various laboratories.
We acquire fresh tissues directly from our collaborative hospitals. The tissues
are promptly fixed (typically within 30 mins of removal) in 10% NBF, and sent to
our tissue array center where they are processed, embedded, sectioned and
validated all under one roof. As a result, our tissue arrays are made from
tissue samples with the following features:
1. Freshly collected (within the past two years);
2. Uniform quality - fixed and processed using the same optimal protocols;
3. Large tissue volumes ensuring lasting supply of the same products.
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Pantomics, Inc.
has a well-equipped tissue
processing center with strict SOPs dedicated to tissue bank services and tissue
array production. |
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The center is optimally set-up
to achieve consistency in tissue processing.
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Optimal fixation and specially
formulated dehydration and embedding procedures lead to production of tissue
blocks with uniform quality |
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With high quality
paraffin-embedded tissues we can create array blocks with various core sizes,
ranging from 1mm to 8mm in any required formats. |
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Stringent QA/QC procedures and
professional design are adapted to ensure the highest tissue array quality. |
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Pantomics currently makes three
major categories of tissue arrays:
1. Arrays for routine IHC controls;
2. Arrays for research and drug discovery;
3. Arrays for education and training. |
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