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Cyclin D1 Rabbit Monoclonal Antibody

Cyclin D1 Rabbit Monoclonal Antibody

$250.00Price
Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. Cyclin D1 antibody is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.

  • Intended Use

    For research use only. For IHC use on formalin-fixed, paraffin-embedded tissue sections.

  • Targets

    Cyclin D1

  • cell Localization

    Nuclear

  • Marker For

    Mantle cell lymphoma

  • Pathology Field

    Hematopathology

  • Control Tissues

    tonsil, mantle cell lymphoma, CyclinD1IHC-TMA

  • References

    1. Inaba T, et al.: Genomics 1992, 13:565-574
    2. Bala S, et al.: Cancer Res 2001, 61:6042-6045
    3. Motokura T, et al.: Genes Chromosomes Cancer 1993, 7:89-95
    4. Pruneri G, et al.: Appl Immunohistochem Mol Morphol 2005, 13:318-322
    5. Dabbs DJ. Diagnostic Immunohistochemistry 2010; Churchill LivingĀ¬stone

  • **

    We also provide Cyclin D1 antibody for IHC staining at $30 - $50 per slide (more information).

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