Tissue cross reactivity (TCR) examination

Tissue cross reactivity (TCR) examination

For all new therapeutic antibodies, it is required by regulatory agencies to assess their safety by examining and identifying their potential cross reactivity (TCR) on a panel of 33 normal tissue types from at least three individuals. Following FDA recommendations, we can provide IHC based-TCR examination on: 1. Single tissue sections of 33 normal tissue types on three or more individuals; 2. Low cost TMA of 33 normal tissue types on one individual (MNO341)l; 3. TMA of 33 normal tissue types in duplicates (MNO661); 4. TMA of 33 normal tissue types of three individuals (MNO961 or MNO1021); 5. *Frozen TMA of 33 normal tissue types of one individual (total three sets of TMA from three individuals). �*� � under development.
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