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SKD241

Skin disease tissue array, 24 cases of normal, reactive and tumor tissues of the skin

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Images

Data Sheet

TNM Grading

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$201

1 slide

In-Stock

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TNM Classification : Malignant melanoma of skin

 

T- Primary tumor

TX - Primary tumor cannot be assessed

TO - No evicence of primary tumor

Tis - Melanoma in situ (Clark level I), (atypical melanocytic hyperplasia, severe melanocytic dysplasia, not an invasive malignant lesion)

T1 - Tumor 0.75 mm or less in thickness and invades the papillary dermis (Clark level II) 

T2    - Tumor more than 0.75 mm but not more than 1.5 mm in thiskness and.or invades to the papillary-reticular dermis interface (Clark level III) 

T3 - Tumor more than 1.5 mm but not more than 4.0 mm in the thiskness, and/or invades the reticular dermis (Clark level IV)

T3a - Tumor more than 1.5 mm but not more than 3.0 mm in thiskness 

T3b - Tumor more than 3.0 mm but not more than 4.0 mm in thiskness 

T4 - Tumor more than 4.0 mm in thiskness, and/or invades subcutanesous tissue (Clark level V) and/or satellite(s) within 2 cm of the primary tumor

T4a - Tumor more than 4.0 mm in thickness and/or invades subcutanesous tissue T4b - Satellite(s) within 2 cm of the primary tumor


Notes: in case of discrepancy between tumor thickness and level, the T category is based on the less favorable finding.


N - Regional lymph nodes

NX - Regional lymph nodes cannot be assessed NO - No regional lymph node metastasis

N1 - Metastasis 3 cm or less in greatest dimension in any regional lymph node(s) N2 - Metastasis more than 3 cm in greatest dimension in any regional lymph node(s) and/or in-transit metastasis

N2a - Metastasis more than 3 cm in greatest dimension in any regional lymph node(s)

N2b - In-transit metastasis

N2c - Both


M - Distant metastasis

MX - Distant metastasis cannot be assessed MO - No distant metastasis M1 - Distant metastasis

M1a - Metastasis in skin or subcutaneous tissue or lymph node(s) beyond the regional lymph nodes

M1b - Visceral metastasis

Species

Human

Cases

24

Cores

24

Core Diameter

2.5mm

Core Thickness

4um

Rows

4

Columns

6

Tissue Type

Paraffin

Notes:

All tissues were fixed in 10% neutral buffered formalin for 24 hours and processed using identical SOPs. Sections were picked onto Superfrost Plus or Startfrost Adhesive slides. They all have a guaranteed six month shelf-life at 4C from the date of shipment. Additional cores not listed are orientation markers and have no data. There maybe <5% core loss per slide but the core retention rate should be >90%.

Bake at 60C for 30 minutes before use. If antigen retrieving is needed, it is always a good idea to start with a protocol with weak to mild strength. Please check our TNM guide as a reference. For IHC related information on products that provide them, please contact us at info@pantomics.com for the most up-to-date information.

Recommended Application

For research use only. Designed for IHC or ISH based protein or RNA tissue profiling in various skin diseases.

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ARRAY POSITION
IMAGE
SEX
AGE
ANATOMIC SITE
PATHOLOGY
GRADE
STAGE (TNM)
A01
M
43
Skin
Normal
A02
M
50
Skin
Normal
A03
M
57
Skin, wrist
Chronic ulcer
A04
M
32
Skin
Inflammation, chronic
A05
M
58
Skin
Ulcer, granuloma
A06
F
68
Skin
Epidermal cyst
B01
F
70
Skin
Skin tag
B02
M
37
Skin
Scar
B03
M
12
Skin
Keratoacanthoma
B04
M
74
Skin
Keratoacanthoma
B05
F
63
Skin, head
Seborrheic keratosis
B06
M
20
Skin
Psoriasis
C01
F
20
Skin, vulva
Condyloma acuminata (HPV+)
C02
M
50
Anus
Condyloma acuminata
C03
F
21
Skin, scalp
Compound nevus
C04
F
19
Skin, scalp
Compound nevus
C05
F
64
Skin
verrucous nevus
C06
M
10M
Skin
Hemangioma
D01
F
24
Skin, scalp
Neurofibroma
D02
F
80
Skin
Dermal cylindroma
D03
M
62
Skin
Basal cell carcinoma
T3N0M0
D04
M
67
Skin
Squamous cell carcinoma
II
T1N0M0
D05
F
64
Scalp, subcutaneous tissue
Plasmacytoma
T1N0M0
D06