Heterogeneity and inconsistency are the two major problems of the tissue arrays made from donor paraffin-embedded tissue blocks that are collected from multiple pathology centers. These problems are closely associated with different fixation and processing methods/standards applied in various laboratories.
We acquire fresh tissues directly from our collaborative hospitals. The tissues are promptly fixed (typically within 30 mins of removal) in 10% NBF, and sent to our tissue array center where they are processed, embedded, sectioned and validated all under one roof. As a result, our tissue arrays are made from tissue samples with the following features:
1. Collected under strict guidelines
2. Uniform quality - fixed and processed using the same optimal protocols
3. Large tissue volumes ensuring lasting supply of the same products
Pantomics, Inc. has a well-equipped tissue processing center with strict SOPs dedicated to tissue bank services and tissue array production.
The center is optimally set-up to achieve consistency in tissue processing
Optimal fixation and specially formulated dehydration and embedding procedures lead to production of tissue blocks with uniform quality
With high quality paraffin-embedded tissues we can create array blocks with various core sizes, ranging from 1mm to 8mm in any required formats.
Stringent QA/QC procedures and professional design are adapted to ensure the highest tissue array quality.
Pantomics currently makes three major categories of tissue arrays:
1. Arrays for IHC/ISH/FISH controls;
2. Arrays for research and drug discovery;
3. Arrays for education and training.